Publications

Publications 2018

Papers including work performed in the frame of iGE3

Alphabetical order of first authors’ names

  • Ansar M, Chung HL, Taylor RL, Nazir A, Imtiaz S, Sarwar MT, Manousopoulou A, Makrythanasis P, Saeed S, Falconnet E, Guipponi M, Pournaras CJ, Ansari MA, Ranza E, Santoni FA, Ahmed J, Shah I, Gul K, Black GC, Bellen HJ, Antonarakis SE. Bi-allelic loss-of-function variants in DNMBP cause infantile cataracts. Am J Hum Genet. 2018 Oct 4;103(4):568-578. ► Pubmed
  • Ansar M, Chung H, Waryah YM, Makrythanasis P, Falconnet E, Rao AR, Guipponi M, Narsani AK, Fingerhut R, Santoni FA, Ranza E, Waryah AM, Bellen HJ, Antonarakis SE. Visual impairment and progressive phthisis bulbi caused by recessive pathogenic variant in MARK3. Hum Mol Genet. 2018 Aug 1;27(15):2703-2711. ► Pubmed
  • Ansar M, Riazuddin S, Sarwar MT, Makrythanasis P, Paracha SA, Iqbal Z, Khan J, Assir MZ, Hussain M, Razzaq A, Polla DL, Taj AS, Holmgren A, Batool N, Misceo D, Iwaszkiewicz J, de Brouwer APM, Guipponi M, Hanquinet S, Zoete V, Santoni FA, Frengen E, Ahmed J, Riazuddin S, van Bokhoven H, Antonarakis SE. Biallelic variants in LINGO1 are associated with autosomal recessive intellectual disability, microcephaly, speech and motor delay. Genet Med. 2018 Jul;20(7):778-784. ► Pubmed
  • Arongaus AB, Chen S, Pireyre M, Glöckner N, Galvão VC, Albert A, Winkler JB, Fankhauser C, Harter K, Ulm R. Arabidopsis RUP2 represses UVR8-mediated flowering in noninductive photoperiods. Genes Dev. 2018 Oct 1;32(19-20):1332-1343. ► Pubmed
  • Beccari L, Moris N, Girgin M, Turner DA, Baillie-Johnson P, Cossy AC, Lutolf MP, Duboule D, Arias AM. Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids. Nature. 2018 Oct;562(7726):272-276. ► Pubmed
  • Branco C, Velasco M, Benguigui M, Currat M, Ray N, Arenas M. Consequences of diverse evolutionary processes on american genetic gradients of modern humans. Heredity (Edinb). 2018 Dec;121(6):548-556. ► Pubmed
  • Bruzzone MJ, Grünberg S, Kubik S, Zentner GE, Shore D. Distinct patterns of histone acetyltransferase and Mediator deployment at yeast protein-coding genes. Genes Dev. 2018 Sep 1;32(17-18):1252-1265. ► Pubmed
  • Buhler S, Nunes JM, Sanchez-Mazas A. Correction to: HLA class I molecular variation and peptide-binding properties suggest a model of joint divergent asymmetric selection. Immunogenetics. 2018 Feb;70(2):141. ► Pubmed
  • Buzgariu W, Wenger Y, Tcaciuc N, Catunda-Lemos AP, Galliot B. Impact of cycling cells and cell cycle regulation on Hydra regeneration. Dev Biol. 2018 Jan 15;433(2):240-253. ► Pubmed
  • Cárdenas A, Villalba A, de Juan Romero C, Picó E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V. Evolution of cortical neurogenesis in amniotes controlled by Robo signaling levels. Cell. 2018 Jul 26;174(3):590-606.e21. ► Pubmed
  • Černý V, Kulichová I, Poloni ES, Nunes JM, Pereira L, Mayor A, Sanchez-Mazas A. Genetic history of the African Sahelian populations. HLA. 2018 Mar;91(3):153-166. ► Pubmed
  • Chahtane H, Nogueira Füller T, Allard PM, Marcourt L, Ferreira Queiroz E, Shanmugabalaji V, Falquet J, Wolfender JL, Lopez-Molina L. The plant pathogen Pseudomonas aeruginosa triggers a DELLA-dependent seed germination arrest in Arabidopsis. Elife. 2018 Aug 28;7. pii: e37082. ► Pubmed
  • Challal D, Barucco M, Kubik S, Feuerbach F, Candelli T, Geoffroy H, Benaksas C, Shore D, Libri D. General regulatory factors control the fidelity of transcription by restricting non-coding and ectopic initiation. Mol Cell. 2018 Dec 20;72(6):955-969.e7. ► Pubmed
  • Cigliola V, Ghila L, Thorel F, van Gurp L, Baronnier D, Oropeza D, Gupta S, Miyatsuka T, Kaneto H, Magnuson MA, Osipovich AB, Sander M, Wright CEV, Thomas MK, Furuyama K, Chera S, Herrera PL. Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells. Nat Cell Biol. 2018 Nov;20(11):1267-1277. ► Pubmed
  • Citi S. Intestinal barriers protect against disease. Science. 2018 Mar 9;359(6380):1097-1098. ► Pubmed
  • Colom A, Derivery E, Soleimanpour S, Tomba C, Molin MD, Sakai N, González-Gaitán M, Matile S, Roux A. A fluorescent membrane tension probe. Nat Chem. 2018 Nov;10(11):1118-1125. ► Pubmed
  • Corre J, van Zessen R, Loureiro M, Patriarchi T, Tian L, Pascoli V, Lüscher C. Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement. Elife. 2018 Oct 30;7. pii: e39945. ► Pubmed
  • Delaney K, Mailler J, Wenda JM, Gabus C, Steiner FA. Differential expression of histone H3.3 genes and their role in modulating temperature stress response in Caenorhabditis elegans. Genetics. 2018 Jun;209(2):551-565. ► Pubmed
  • Demarsy E, Goldschmidt-Clermont M, Ulm R. Coping with 'dark sides of the sun' through photoreceptor signaling. Trends Plant Sci. 2018 Mar;23(3):260-271. ► Pubmed
  • Dibner C, Schibler U. Body clocks: Time for the Nobel Prize. Acta Physiol (Oxf). 2018 Feb;222(2). ► Pubmed
  • Espitia Jaimes C, Fish RJ, Neerman-Arbez M. Local chromatin interactions contribute to expression of the fibrinogen gene cluster. J Thromb Haemost. 2018 Oct;16(10):2070-2082. ► Pubmed
  • Fabbiano S, Suárez-Zamorano N, Chevalier C, Lazarević V, Kieser S, Rigo D, Leo S, Veyrat-Durebex C, Gaïa N, Maresca M, Merkler D, Gomez de Agüero M, Macpherson A, Schrenzel J, Trajkovski M. Functional gut microbiota remodeling contributes to the caloric restriction-induced metabolic improvements. Cell Metab. 2018 Dec 4;28(6):907-921.e7. ► Pubmed
  • Gabay C, Fautrel B, Rech J, Spertini F, Feist E, Kötter I, Hachulla E, Morel J, Schaeverbeke T, Hamidou MA, Martin T, Hellmich B, Lamprecht P, Schulze-Koops H, Courvoisier DS, Sleight A, Schiffrin EJ. Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still's disease. Ann Rheum Dis. 2018 Jun;77(6):840-847. ► Pubmed
  • Galliot B, Buzgariu W, Schenkelaars Q, Wenger Y. Non-developmental dimensions of adult regeneration in Hydra. Int J Dev Biol. 2018;62(6-7-8):373-381. ► Pubmed
  • Garieri M, Stamoulis G, Blanc X, Falconnet E, Ribaux P, Borel C, Santoni F, Antonarakis SE. Extensive cellular heterogeneity of X inactivation revealed by single-cell allele-specific expression in human fibroblasts. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13015-13020. ► Pubmed
  • Goeury T, Creary LE, Fernandez-Vina MA, Tiercy JM, Nunes JM, Sanchez-Mazas A. Mandenka from Senegal: Next Generation Sequencing typings reveal very high frequencies of particular HLA class II alleles and haplotypes. HLA. 2018 Feb;91(2):148-150. ► Pubmed
  • Govindan S, Oberst P, Jabaudon D. In vivo pulse labeling of isochronic cohorts of cells in the central nervous system using FlashTag. Nat Protoc. 2018 Oct;13(10):2297-2311. ► Pubmed
  • Hafner L, Lezaja A, Zhang X, Lemmens L, Shyian M, Albert B, Follonier C, Nunes JM, Lopes M, Shore D, Mattarocci S. Rif1 binding and control of chromosome-internal DNA replication origins is limited by telomere sequestration. Cell Rep. 2018 Apr 24;23(4):983-992. ► Pubmed
  • Hurst SA, Zellweger U, Bosshard G, Bopp M; Swiss Medical End-of-Life Decisions Study Group. Medical end-of-life practices in Swiss cultural regions: a death certificate study. BMC Med. 2018 Apr 20;16(1):54. ► Pubmed
  • Jørgensen MM, Ekundayo B, Zaratiegui M, Skriver K, Thon G, Schalch T. Structure of the replication regulator Sap1 reveals functionally important interfaces. Sci Rep. 2018 Jul 19;8(1):10930. ► Pubmed
  • Kubik S, O'Duibhir E, de Jonge WJ, Mattarocci S, Albert B, Falcone JL, Bruzzone MJ, Holstege FCP, Shore D. Sequence-directed action of RSC remodeler and general regulatory factors modulates +1 nucleosome position to facilitate transcription. Mol Cell. 2018 Jul 5;71(1):89-102.e5. ► Pubmed
  • Macheret M, Halazonetis TD. Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress. Nature. 2018 Mar 1;555(7694):112-116. ► Pubmed
  • Martins AF, Bennett NC, Clavel S, Groenewald H, Hensman S, Hoby S, Joris A, Manger PR, Milinkovitch MC. Locally-curved geometry generates bending cracks in the African elephant skin. Nat Commun. 2018 Oct 2;9(1):3865. ► Pubmed
  • Molinard-Chenu A, Dayer A. The candidate schizophrenia risk gene DGCR2 regulates early steps of corticogenesis. Biol Psychiatry. 2018 Apr 15;83(8):692-706. ► Pubmed
  • Nikolaev SI, Vetiska S, Bonilla X, Boudreau E, Jauhiainen S, Rezai Jahromi B, Khyzha N, DiStefano PV, Suutarinen S, Kiehl TR, Mendes Pereira V, Herman AM, Krings T, Andrade-Barazarte H, Tung T, Valiante T, Zadeh G, Tymianski M, Rauramaa T, Ylä-Herttuala S, Wythe JD, Antonarakis SE, Frösen J, Fish JE, Radovanovic I. Somatic activating KRAS mutations in arteriovenous malformations of the brain. N Engl J Med. 2018 Jan 18;378(3):250-261. ► Pubmed
  • Niquille M, Limoni G, Markopoulos F, Cadilhac C, Prados J, Holtmaat A, Dayer A. Neurogliaform cortical interneurons derive from cells in the preoptic area. Elife. 2018 Mar 20;7. pii: e32017. ► Pubmed
  • Nussberger B, Currat M, Quilodran CS, Ponta N, Keller LF. Range expansion as an explanation for introgression in European wildcats. Biological Conservation, Volume 218, February 2018, Pages 49-5. ► ScienceDirect
  • Pascoli V, Hiver A, Van Zessen R, Loureiro M, Achargui R, Harada M, Flakowski J, Lüscher C. Stochastic synaptic plasticity underlying compulsion in a model of addiction. Nature. 2018 Dec;564(7736):366-371. ► Pubmed
  • Petrenko V, Dibner C. Cell-specific resetting of mouse islet cellular clocks by glucagon, glucagon-like peptide 1 and somatostatin. Acta Physiol (Oxf). 2018 Apr;222(4):e13021. ► Pubmed
  • Petrenko V, Philippe J, Dibner C. Time zones of pancreatic islet metabolism. Diabetes Obes Metab. 2018 Sep;20 Suppl 2:116-126. ► Pubmed
  • Podolec R, Ulm R. Photoreceptor-mediated regulation of the COP1/SPA E3 ubiquitin ligase. Curr Opin Plant Biol. 2018 Oct;45(Pt A):18-25. ► Pubmed
  • Popadin K, Peischl S, Garieri M, Sailani MR, Letourneau A, Santoni F, Lukowski SW, Bazykin GA, Nikolaev S, Meyer D, Excoffier L, Reymond A, Antonarakis SE. Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection. Genome Res. 2018 Jan;28(1):1-10. doi: 10.1101/gr.228411.117. ► Pubmed
  • Prouteau M, Loewith R. Regulation of cellular metabolism through phase separation of enzymes. Biomolecules. 2018 Dec 3;8(4). pii: E160. ► Pubmed
  • Quilodrán CS, Austerlitz F, Currat M, Montoya-Burgos JI. Cryptic biological invasions: a general model of hybridization. Sci Rep. 2018 Feb 5;8(1):2414. ► Pubmed
  • Quilodrán CS, Currat M, Montoya-Burgos JI. Effect of hybridization with genome exclusion on extinction risk. Conserv Biol. 2018 Oct;32(5):1139-1149. ► Pubmed
  • Riggi M, Niewola-Staszkowska K, Chiaruttini N, Colom A, Kusmider B, Mercier V, Soleimanpour S, Stahl M, Matile S, Roux A, Loewith R. Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2. Nat Cell Biol. 2018 Sep;20(9):1043-1051. ► Pubmed
  • Rivera-Rivera CJ, Montoya-Burgos JI. Back to the roots: Reducing evolutionary rate heterogeneity among sequences gives support for the early morphological hypothesis of the root of Siluriformes (Teleostei: Ostariophysi). Mol Phylogenet Evol. 2018 Oct;127:272-279. ► Pubmed
  • Sadowski SM, Pusztaszeri M, Brulhart-Meynet MC, Petrenko V, De Vito C, Sobel J, Delucinge-Vivier C, Kebebew E, Regazzi R, Philippe J, Triponez F, Dibner C. Identification of differential transcriptional patterns in primary and secondary hyperparathyroidism. J Clin Endocrinol Metab. 2018 Jun 1;103(6):2189-2198. ► Pubmed
  • Shah J, Rouaud F, Guerrera D, Vasileva E, Popov LM, Kelley WL, Rubinstein E, Carette JE, Amieva MR, Citi S. A dock-and-lock mechanism clusters ADAM10 at cell-cell junctions to promote α-toxin cytotoxicity. Cell Rep. 2018 Nov 20;25(8):2132-2147.e7. ► Pubmed
  • Shanmugabalaji V, Chahtane H, Accossato S, Rahire M, Gouzerh G, Lopez-Molina L, Kessler F. Chloroplast biogenesis controlled by DELLA-TOC159 interaction in early plant development. Curr Biol. 2018 Aug 20;28(16):2616-2623.e5. ► Pubmed
  • Silva NM, Rio J, Kreutzer S, Papageorgopoulou C, Currat M. Bayesian estimation of partial population continuity using ancient DNA and spatially explicit simulations. Evol Appl. 2018 Jul 3;11(9):1642-1655. ► Pubmed
  • Soudet J, Gill JK, Stutz F. Noncoding transcription influences the replication initiation program through chromatin regulation. Genome Res. 2018 Dec;28(12):1882-1893. ► Pubmed
  • Stévant I, Nef S. Single cell transcriptome sequencing: A new approach for the study of mammalian sex determination. Mol Cell Endocrinol. 2018 Jun 15;468:11-18. ► Pubmed
  • Stévant I, Neirijnck Y, Borel C, Escoffier J, Smith LB, Antonarakis SE, Dermitzakis ET, Nef S. Deciphering cell lineage specification during male sex determination with single-cell RNA sequencing. Cell Rep. 2018 Feb 6;22(6):1589-1599. ► Pubmed
  • Stévant I, Papaioannou MD, Nef S. A brief history of sex determination. Mol Cell Endocrinol. 2018 Jun 15;468:3-10. ► Pubmed
  • Tas D, Stickley L, Miozzo F, Koch R, Loncle N, Sabado V, Gnägi B, Nagoshi E. Parallel roles of transcription factors dFOXO and FER2 in the development and maintenance of dopaminergic neurons. PLoS Genet. 2018 Mar 12;14(3):e1007271. ► Pubmed
  • Trofimov V, Kicka S, Mucaria S, Hanna N, Ramon-Olayo F, Del Peral LV, Lelièvre J, Ballell L, Scapozza L, Besra GS, Cox JAG, Soldati T. Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets. Sci Rep. 2018 Mar 2;8(1):3939. ► Pubmed
  • Vasileva E, Citi S. The role of microtubules in the regulation of epithelial junctions. Tissue Barriers. 2018;6(3):1539596. ► Pubmed
  • Viñuela A, Brown AA, Buil A, Tsai PC, Davies MN, Bell JT, Dermitzakis ET, Spector TD, Small KS. Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort. Hum Mol Genet. 2018 Feb 15;27(4):732-741. ► Pubmed
  • Vitali I, Fièvre S, Telley L, Oberst P, Bariselli S, Frangeul L, Baumann N, McMahon JJ, Klingler E, Bocchi R, Kiss JZ, Bellone C, Silver DL, Jabaudon D. Progenitor hyperpolarization regulates the sequential generation of neuronal subtypes in the developing neocortex. Cell. 2018 Aug 23;174(5):1264-1276.e15. ► Pubmed

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