MSc position

Circadian Endocrinology Lab - Dr. Charna Dibner

Department of Internal Medicine Specialty
& Department of Cell Physiology and Metabolism
Faculty of Medicine

The Dibner’s group studies the impact of biological clocks on metabolism, with particular focus on the roles of circadian oscillator in pancreatic islet and skeletal muscle function in physiology, and in etiology of obesity and type 2 diabetes.

We are looking for an ambitious MSc candidate, highly motivated and responsible, interested in working with mammalian, in particular human, primary cell cultures for the ongoing project, focusing on the input of human skeletal muscle clock into the lipid homeostasis, myokine secretion, and insulin sensitivity.

The study is performed in a close collaboration with the laboratory of Prof. Howard Riezman, Department of Biochemistry. The working languages in the laboratory are French and English. French skills, although helpful, are not essential.

Please send a complete CV including research interests, with a letter of motivation to:

Charna.Dibner@hcuge.ch

Master student position

Laboratory of Sandra Citi
Department of Cell Biology – Faculty of Sciences

Investigating the molecular basis of hypertension

The Citi Laboratory investigates how junctional proteins in epithelial and endothelial cells control signaling, through the cytoskeleton, transcription factors, and membrane proteins. Our laboratory discovered PLEKHA7, a cytoplasmic component of adherens junctions, which binds to paracingulin and to other cytoplasmic junctional proteins to stabilize adherin-based junctions. PLEKHA7 has been found to be involved in cardiovascular physiology, hypertension and glaucome, through Genome-Wide Association Studies and genetic analysis. In rats Knock-Out for PLEKHA7, blood pressure is lower, and there is increased intracellular calcium and NO signaling by endothelial cells.

The proposed project addresses the role of PLEKHA7 in endothelial cells, using CRISPR-KO cellular and mouse models, and state-of-the art biochemical and cell biological techniques, to discover how PLEKHA7 is implicated in hypertension and vascular physiology.

Further information:
Professor Sandra Citi
Sandra.Citi@unige.ch

Master, PhD and post-doctoral positions

Various iGE3 members
  • Master student - Patrick Meraldi Group, Faculty of MedicineAnnouncement
  • Master student - Rabih Murr Group, Faculty of MedicineAnnouncement
  • Master students - Serge Nef Group, Faculty of MedicineAnnouncement
  • Master students - Xavier Perret Group, Faculty of ScienceAnnouncement
  • Master students - Didier Picard Group, Faculty of ScienceAnnouncement
  • Master student - PhD student - Post-doctoral fellows - Paul Guichard, Faculty of ScienceDetails
  • Master students - PhD students - Post-doctoral fellows - Michel Milinkovitch, Faculty of ScienceDetails
  • PhD students - Post-doctoral fellows - Thanos Halazonetis Group, Faculty of ScienceDetails
  • PhD students - Post-doctoral fellows - Robbie Loewith Group, Faculty of ScienceDetails
  • PhD student - Post-doctoral fellow - Florian Steiner Group, Faculty of ScienceDetails
  • Post-doctoral fellows - Jean-Claude Martinou Group, Faculty of ScienceDetails
  • Post-doctoral fellow - Didier Picard Group, Faculty of ScienceDetails